Andrew joined RVL® as a patent agent upon completing his PhD in Biochemistry and Biophysics at the University of North Carolina, Chapel Hill. Andrew’s academic research has focused on the engineering of novel optogenetic tools to study fundamental mechanisms of epigenetic regulation. Andrew has contributed scientific expertise to biotechnology, therapeutics, and medical technology companies large and small. Active in science outreach, he designed a suite of educational activities to teach children and adults about DNA and gene therapy as a Morehead Planetarium and Science Center Ambassador, and has visited classrooms in rural communities to share his passion for science. Andrew’s ability to explain complicated concepts and mechanical and regulatory operations as consultant and teacher is readily apparent in his work as a patent practitioner.
Andrew holds a B.S. in Chemistry from the University of California, Berkeley, and previously worked asa scientist at Bio-Rad. Prior to his scientific career, Andrew was a United States Marine and held a top-secret security clearance as a signals intelligence analyst with the National Security Agency.
Presentations & Publications
- Lerner, Andrew et al. “Engineering improved photoswitches for the control of nucleocytoplasmic distribution.” ACS Synthetic Biology. 15 Nov. 2018. Publication.
- “Elucidating dynamics of histone post-translational modifications using optogenetics.” EpiCypher 2018: Biological and Clinical Frontiers in Epigenetics. Nassau, Bahamas. 7 Nov. 2018. Poster.
- Yumerefendi, Hayretin et al. “Light-dependent cytoplasmic recruitment enhances the dynamic range of a nuclear import photoswitch.” ChemBioChem. 14 Feb. 2018. Publication.
- “Methylation and demethylation: an optogenetic tale of histone tails.” Smaller Eukaryotes Group Meeting, NC Biotechnology Center. Durham, NC. 12 Dec. 2017. Presentation.
- Yumerefendi, Hayretin et al. “Light-induced nuclear export reveals rapid dynamics of epigenetic modifications.” Nature Chemical Biology. 18 Apr. 2016. Publication.